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INDICATIONS : HALOTHANE ANESTHESIA MEDICATIONS ANESTHESIA MEDICATIONS HALOTHANE ANESTHESIA MEDICATIONS
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What is Anesthesia?
An anesthetic (anaesthetic), is a drug that causes anesthesia — reversible loss of sensation. They contrast with analgesics (painkillers), which relieve pain without eliminating sensation. These drugs are generally administered to facilitate surgery. A wide variety of drugs are used in modern anesthetic practice. Many are rarely used outside of anesthesia, although others are used commonly by all disciplines. Anesthetics are categorized in to two classes: general anesthetics, which cause a reversible loss of consciousness, and local anesthetics, which cause a reversible loss of sensation for a limited region of the body while maintaining consciousness. Combinations of anesthetics are sometimes used for their synergistic and additive therapeutic effects, however, adverse effects may also be increased.
More on Halothane Below
- WIKIPEDIA HALOTHANE
Halothane
vapour (trademarked as Fluothane) is an inhalational general anaesthetic. Its IUPAC name is 2-bromo-2-chloro-1,1,1-trifluoroethane. It is the only inhalational anaesthetic agent containing a bromine atom; there are several other halogenated anesthesia agents which lack the bromine atom and do contain the fluorine and chlorine atoms present in halothane.
It is colourless and pleasant-smelling, but unstable in light. It is packaged in dark-coloured bottles and contains 0.01% thymol as a stabilising agent. Halothane is a core medicine in the World Health Organization's "Essential Drugs List", which is a list of minimum medical needs for a basic health care system. Its use in developed countries however has almost entirely been superseded by newer inhalational anaesthetic agents.
Related substances: Chemically,
halothane
is not an ether; it is an alkane. The structure has one stereocentre, so there are (R) and (S) optical isomers. Attempts to find anaesthetics with less metabolism led to halogenated ethers such as enflurane and isoflurane. The incidence of hepatic reactions with these agents is lower. The exact degree of hepatotoxic potential of enflurane is debated, although it is minimally metabolised. Isoflurane is essentially not metabolised and reports of associated liver injury are quite rare. Small amounts of trifluoroacetic acid can be formed from both
halothane
and isoflurane metabolism and possibly accounts for cross sensitisation of patients between these agents.
- WIKIPEDIA
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